JO1 protein (His tag) (80-1375)
Purified recombinant JO1 protein (His tag)
Overview
Overview
| Synonyms | Histidyl-TRNA Synthetase protein, HisRS protein, JO-1 protein, JO 1 protein, HARS protein |
|---|---|
| Species | Human |
| Protein Type | Recombinant |
Specifications
| Residues | 1-509 aa |
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| Expression System | E.coli |
| Grade & Purity | > 90% pure |
| Method of Purification | Purified using proprietary chromatographic techniques |
| Molecular Weight | 57 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied in 50mM Tris buffer, pH 8.0, 300mM NaCl and 2mM DTT |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | JO1 is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. |
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