KCTD11 protein (His tag) (80R-2687)
Purified recombinant KCTD11 protein (His tag)
|Synonyms||BTB/POZ domain-containing protein KCTD11 protein, C17orf36 protein, KCASH1 protein, MGC129844 protein, REN protein, REN/KCTD11 protein, KCTD11, KCTD 11, KCTD-11, KCTD 11 protein, KCTD-11 protein|
SDS-PAGE analysis of KCTD11 protein (His tag) (80R-2687)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-232 aa: MGSSHHHHHH SSGLVPRGSH MLGAMFRAGT PMPPNLNSQG GGHYFIDRDG KAFRHILNFL RLGRLDLPRG YGETALLRAE ADFYQIRPLL DALRELEASQ GTPAPTAALL HADVDVSPRL VHFSARRGPH HYELSSVQVD TFRANLFCTD SECLGALRAR FGVASGDRAE GSPHFHLEWA PRPVELPEVE YGRLGLQPLW TGGPGERREV VGTPSFLEEV LRVALEHGFR LDSVFPDPED LLNSRSLRFV RH|
|Grade & Purity||> 90% pure|
|Molecular Weight||28 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol|
Storage & Safety
|Storage||Can be stored at 4 deg C for short terms (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles|
|Biological Significance||BTB/POZ domain-containing protein KCTD11, is a 232 amino acid regulator of neuronal differentiation that induces growth arrest, apoptosis and the expression of p27, a cyclin-dependent kinase inhibitor. Expressed at highest levels in cerebellum, KCTD11 functions as an antagonist of the Hedgehog pathway and activator of the caspase cascade. Recombinant human KCTD11 protein, fused to His-tag at N-terminus, was expressed in E.coli.|
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