Keratin K18 protein (30R-2128)

Purified native Bovine Keratin K18 Protein

Synonyms Cytokeratin 18 protein, Keratin K 18, Keratin K 18 protein, Keratin K18, Keratin K-18 protein, Keratin K-18, Keratin 18 protein
Species Bovine
Protein Type Native
Applications User optimized

Specifications

Source Bovine liver
Grade & Purity > 95% pure
Molecular Weight 45 kDa
Form & Buffer Supplied in lyophilized form with 30 mM Tris/HCI pH 8, 9 M urea, 2 mM DTT, 2 mM EDTA, 10 mM methylammonium chloride
Concentration 1 mg/ml

Storage & Safety

Storage Store at 2-8 deg C in lyophilized form. Following reconstitution aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.

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Availability: In stock

Price: €224.13
Size: 100 ug
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