Keratin K18 protein (30R-2128)
Purified native Bovine Keratin K18 Protein
Overview
Overview
| Synonyms | Cytokeratin 18 protein, Keratin K 18, Keratin K 18 protein, Keratin K18, Keratin K-18 protein, Keratin K-18, Keratin 18 protein |
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| Species | Bovine |
| Protein Type | Native |
| Applications | User optimized |
Specifications
| Source | Bovine liver |
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| Grade & Purity | > 95% pure |
| Molecular Weight | 45 kDa |
| Form & Buffer | Supplied in lyophilized form with 30 mM Tris/HCI pH 8, 9 M urea, 2 mM DTT, 2 mM EDTA, 10 mM methylammonium chloride |
| Concentration | 1 mg/ml |
Storage & Safety
| Storage | Store at 2-8 deg C in lyophilized form. Following reconstitution aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood. |
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