KIR2DL3 protein (30R-1031)
Purified recombinant Human KIR2DL3 protein
Overview
Overview
| Synonyms | , CD158B2 protein, KIR-2, Killer cell immunoglobulin-like receptor 2DL3 protein, p58 natural killer cell receptor clone CL-6 protein, CD158) protein, KIR2DL3 protein, NKAT2b protein, MHC class I NK cell receptor protein, KIR 2, Killer inhibitory receptor CL2 3 protein, Killer cell immunoglobulin-like receptor 2DL3 CD158b protein, p58 protein, GL183 protein, KIR023GB protein, NKAT-2 protein, Natural Killer Associated Transcript 2 protein, KIR2DL3 (p58 KIR protein, Natural killer-associated transcript 2 protein, KIR 2 protein, MHC Class I NK Cell Receptor protein, KIR2, KIR-2 protein, NKAT2a protein, Killer Cell Immunoglobulin Like Receptor 2DL3 protein, p58 Natural Killer Cell Receptor Clone CL6 protein, NKAT2 protein, p58 NK receptor protein, KIRCL23 protein, p58.2 MHC class-I-specific NK re protein, p58.2 MHC Class I Specific NK Receptor protein |
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| Species | Human |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Images
SDS-PAGE analysis of KIR2DL3 protein (30R-1031)
SDS-PAGE gel analysis of KIR2DL3 protein where the figure is annotated with amount of protein run on the gel.
Specifications
| Residues | MEGVHRKPSL LAHPGPLVKS EETVILQCWS DVRFQHFLLH REGKFKDTLH LIGEHHDGIS KANFSIGPMM QDLAGTYRCY GSVTHSPYQL SAPSDPLDIV ITGLYEKPSL SAQPGPTVLA GESVTLSCSS RSSYDMYHLS REGEAHERRF SAGPKVNGTF QADFPLGPAT HGGTYRCFGS FRDSPYEWSN SSDPLLVSVT GN |
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| Expression System | E.coli |
| Grade & Purity | > 95% pure |
| Molecular Weight | 22.2 kDa (202aa), confirmed by MALDI-TOF. |
| Form & Buffer | Supplied as a liquid in 20 mM Tris-HCl buffer, pH7.5. |
| Concentration | 1 mg/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | An inhibitory Killer Cell Ig-like Receptor(KIR, previously called p58 KIR, cl-6, NKAT2 or KIR-K7), which recognizes class I MHC molecules (HLA-Cw1, -Cw3, -Cw7, and Cw8). The protein coding region of the extracellular domain of KIR2DL3 (amino acid 1-202) was cloned into an E. coli expression vector. The extracellular domain of KIR2DL3 protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer. |
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