KLRC1 antibody (70R-13197)
Affinity purified Rabbit polyclonal KLRC1 antibody
Overview
Overview
| Synonyms | Polyclonal KLRC1 antibody, Anti-KLRC1 antibody, KLRC-1 antibody, NKG2-A/NKG2-B type II integral membrane protein antibody, KLRC1 antibody, CD159A antibody, NKG2A antibody, KLRC1, NKG2 antibody, C-lectin type II protein antibody, KLRC 1, MGC59791 antibody, CD159 antigen-like family member A antibody, NKG2-A/B-activating NK receptor antibody, KLRC-1, MGC13374 antibody, NKG2-A/B type II integral membrane protein antibody, KLRC 1 antibody |
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| Cross Reactivity | Human |
| Applications | ICC, IF, WB |
Images
Specifications
| Host | Rabbit |
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| Isotype | IgG |
| Method of Purification | KLRC1 antibody was purified by antigen-affinity chromatography |
| Molecular Weight | 26 kDa |
| Form & Buffer | Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative. |
| Concentration | 0.54 mg/ml |
Usage & Assay Information
| Usage Recommendations | IF:1:100-1:500, ICC:1:100-1:500, WB: 1:500-1:3000 |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Natural killer cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. |
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