Immunofluorescent staining using KPNA4 antibody (70R-12988)
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using QIP1 antibody at 1:200 dilution.
KPNA4 antibody
Immunofluorescent staining using KPNA4 antibody (70R-12988)
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using QIP1 antibody at 1:200 dilution.
Western blot analysis using KPNA4 antibody (70R-12988)
Western blot analysis of 30 ug of whole cell lysate (A: 293T; B: HepG2; C: Molt-4) using a 7.5 % SDS PAGE gel and KPNA4 antibody at a dilution of 1:1500
Immunohistochemical staining using KPNA4 antibody (70R-12988)
Immunohistochemical staining of paraffin-embedded H1299 xenograft using KPNA4 antibody at a dilution of 1:500
Specifications
Host
Rabbit
Isotype
IgG
Method of Purification
KPNA4 antibody was purified by antigen-affinity chromatography
Molecular Weight
58 kDa
Form & Buffer
Supplied as a concentrated soloution containing 1X PBS, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
General Information
Biological Significance
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.