LCN2 protein (80R-4231)
Recombinant Mouse LCN2 protein with His tag
Overview
Overview
| Synonyms | Mouse LCN2 protein, Recombinant LCN2 protein, Neutrophil gelatinase-associated lipocalin protein, 24p3 protein, AW212229 protein, Sip24 protein |
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| Species | Mouse |
| Protein Type | Recombinant |
| Applications | Control, SDS-PAGE |
Images
Coomassie blue stained SDS-PAGE showing analysis of LCN2 protein(80R-4231)
Figure annotation denotes ug of protein loaded and % gel used.
Specifications
| Residues | 21-200 amino acids of Mouse LCN2 protein: MGSSHHHHHH SSGLVPRGSH MGSQDSTQNL IPAPSLLTVP LQPDFRSDQF RGRWYVVGLA GNAVQKKTEG SFTMYSTIYE LQENNSYNVT SILVRDQDQG CRYWIRTFVP SSRAGQFTLG NMHRYPQVQS YNVQVATTDY NQFAMVFFRK TSENKQYFKI TLYGRTKELS PELKERFTRF AKSLGLKDDN IIFSVPTDQC IDN |
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| Expression System | E.coli |
| Grade & Purity | > 85% pure |
| Molecular Weight | 23.3 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied as liquid in PBS (pH 7.4) containing 10% glycerol and 1mM DTT |
| Concentration | 500 ug/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term. For long term storage, aliquot and store at -20 deg C. Avoid repeated freeze thaw cycles. |
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General Information
| Biological Significance | Lcn2 also known as neutrophil gelatinase-associated lipocalin, belongs to the calycin superfamily and Lipocalin family. LCN2 is an iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. The binding of LCN2 to bacterial siderophores is important in the innate immune response to bacterial infection. Also LCN2 functions as a growth factor. LCN2 is strongly upregulated during inflammation and is upregulated by interleukin 1 (but not TNF alpha) in humans. Recombinant mouse Lcn2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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