Lcn2 protein (80R-4313)
Purified Recombinant Lcn2 protein (His tagged)
Overview
Overview
| Synonyms | Sip24 protein |
|---|---|
| Species | Rat |
| Protein Type | Recombinant |
| Applications | SDS-PAGE |
Images
SDS-PAGE analysis using Lcn2 protein (His tag) (80R-4313)
Figure annotation denotes ug of protein loaded and % gel used.
Specifications
| Residues | 21-198 aa |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 95% pure |
| Molecular Weight | 22.9 kDa |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied in liquid form in PBS buffer (pH 7.4) containing 20% glycerol |
| Concentration | 250 ug/ml |
Storage & Safety
| Storage | Store at 4 deg C for short term storage. For long term storage, aliquot and store at -20 or -70 deg C. Avoid repeat freeze/thaw cycles |
|---|
General Information
| Biological Significance | Lcn2 also known as Neutrophil gelatinase-associated lipocalin. It belongs to the calycin superfamily and Lipocalin family. It is essential component of the antimicrobial innate immune system, is present in neutrophils and multiple other tissues. It prevents iron acquisition by microorganisms by sequestering iron-loaded bacterial siderophores. In contrast to its pro-apoptotic activity, Lcn2 has also been reported to be a survival factor. Lcn2 protected thyroid carcinoma cells from apoptosis induced by serum deprivation and silencing of Lcn2 reduced thyroid tumor growth. Recombinant rat Lcn2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
|---|
Reviews
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product