Lcn2 protein (80R-4313)

Purified Recombinant Lcn2 protein (His tagged)

Synonyms Sip24 protein
Species Rat
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis using Lcn2 protein (His tag) (80R-4313)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 21-198 aa
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 22.9 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in PBS buffer (pH 7.4) containing 20% glycerol
Concentration 250 ug/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage, aliquot and store at -20 or -70 deg C. Avoid repeat freeze/thaw cycles

General Information

Biological Significance Lcn2 also known as Neutrophil gelatinase-associated lipocalin. It belongs to the calycin superfamily and Lipocalin family. It is essential component of the antimicrobial innate immune system, is present in neutrophils and multiple other tissues. It prevents iron acquisition by microorganisms by sequestering iron-loaded bacterial siderophores. In contrast to its pro-apoptotic activity, Lcn2 has also been reported to be a survival factor. Lcn2 protected thyroid carcinoma cells from apoptosis induced by serum deprivation and silencing of Lcn2 reduced thyroid tumor growth. Recombinant rat Lcn2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

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Images

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SDS-PAGE analysis using Lcn2 protein (His tag) (80R-4313)



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Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €224.95
Size: 20 ug
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