Leptin antibody (10-7820)
Mouse monoclonal Leptin antibody
Overview
Overview
| Synonyms | Monoclonal Leptin antibody, Anti-Leptin antibody, OB antibody, Obesity antibody, Obesity antibody, Leptin antibody, Anti Leptin antibody, OB antibody |
|---|---|
| Specificity | Human leptin |
| Applications | ELISA, Immunoassays |
| Immunogen | Leptin antibody was raised in mouse using highly pure recombinant human leptin as the immunogen. |
| Assay Information | 10-7820 can be used in a sandwich immunoassay as a coating antibody in conjunction with 10-7821 or 10-7822 as the conjugate antibody |
Specifications
| Host | Mouse |
|---|---|
| Clone | M18612LP1 |
| Isotype | IgG1 |
| Form & Buffer | Supplied in PBS, pH 7.4, 0.1 % sodium azide (NaN3) |
Storage & Safety
| Storage | Store at 4 deg C. |
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General Information
| Biological Significance | Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. |
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