Western blot analysis using LETM1 antibody (70R-13492)
Western blot analysis of 50 ug of whole cell lysate (A: Mouse brain) using a 7.5 % SDS PAGE gel and LETM1 antibody at a dilution of 1:1000
LETM1 antibody
Western blot analysis using LETM1 antibody (70R-13492)
Western blot analysis of 50 ug of whole cell lysate (A: Mouse brain) using a 7.5 % SDS PAGE gel and LETM1 antibody at a dilution of 1:1000
Western blot analysis using LETM1 antibody (70R-13492)
Western blot analysis of 30 ug of whole cell lysate (A: A431; B: H1299; C: Hela; D: Hep G2) using a 7.5 % SDS PAGE gel and LETM1 antibody at a dilution of 1:1000
Immunofluorescent staining using LETM1 antibody (70R-13492)
Immunofluorescence analysis of methanol-fixed A431, using LETM1 antibody at 1:200 dilution.
Immunohistochemical staining using LETM1 antibody (70R-13492)
Immunohistochemical staining of paraffin-embedded HSC3 xenograft using LETM1 antibody at a dilution of 1:500
Specifications
Host
Rabbit
Isotype
IgG
Method of Purification
LETM1 antibody was purified by antigen-affinity chromatography
Molecular Weight
83 kDa
Form & Buffer
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
General Information
Biological Significance
This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19.