LGALS7 protein (His tag) (80R-1744)
Purified recombinant Human LGALS7 protein
|Synonyms||Galectin7 protein, LGALS-7, LGALS7A protein, LGALS 7 protein, LGALS 7, LGALS-7 protein, GAL7 protein, LGALS7|
Coomassie Blue stained SDS-PAGE of LGALS7 protein (His tag) (80R-1744)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-136 amino acids: MGSSHHHHHH SSGLVPRGSH MSNVPHKSSL PEGIRPGTVL RIRGLVPPNA SRFHVNLLCG EEQGSDAALH FNPRLDTSEV VFNSKEQGSW GREERGPGVP FQRGQPFEVL IIASDDGFKA VVGDAQYHHF RHRLPLARVR LVEVGGDVQL DSVRIF|
|Grade & Purity||> 95% pure|
|Molecular Weight||17.2 kDa (156aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol and 1mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||LGALS7, also known as galectin 7, is a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Members of this family have been implicated in a variety of functions, including growth regulation, cell adhesion, migration, neoplastic transformation, and immune responses. It is expressed mainly in stratified squamous epithelium, LGALS7 protein is activated by p53 and repressed by retinoic acid. It is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. Recombinant human LGALS7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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