LGALSL protein (His tag) (80R-2685)
Purified recombinant LGALSL protein (His tag)
|Synonyms||Galectin-related protein protein, GRP protein, HSPC159 protein, LGALSL|
SDS-PAGE analysis of LGALSL protein (His tag) (80R-2685)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-172 aa: MGSSHHHHHH SSGLVPRGSH MGSMAGSVAD SDAVVKLDDG HLNNSLSSPV QADVYFPRLI VPFCGHIKGG MRPGKKVLVM GIVDLNPESF AISLTCGDSE DPPADVAIEL KAVFTDRQLL RNSCISGERG EEQSAIPYFP FIPDQPFRVE ILCEHPRFRV FVDGHQLFDF YHRIQTLSAI DTIKINGDLQ ITKLG|
|Grade & Purity||> 90% pure|
|Molecular Weight||21.4 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT|
Storage & Safety
|Storage||Can be stored at 4 deg C for short terms (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles|
|Biological Significance||Galectin-related protein, also known as LGALSL, is a 172 amino acid protein that contains one galectin domain. Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and also play a role in tumor progression, pre-mRNA splicing and apoptosis. However, LGALSL does not appear to bind carbohydrates or lactose because the critical residues required for binding are not conserved. Recombinant human LGALSL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
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