LIGHT protein (30R-AL019)

Purified recombinant Human LIGHT protein

Synonyms TNFSF14 protein, HVEM-L protein, TNF14 protein, Ligand for herpesvirus entry mediator protein, CD258 protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of LIGHT protein corresponding to amino acids MRLHQRLGDI VAHLPDGGKG SWEKLIQDQR SHQANPAAHL TGANASLIGI GGPLLWETRL GLAFLRGLTY HDGALVTMEP GYYYVYSKVQ LSGVGCPQGL ANGLPITHGL YKRTSRYPKE LELLVSRRSP CGRANSSRVW WDSSFLGGVV HLEAGEEVVV RVPGNRLVRP RDGTRSYFGA FMV.
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 20.1 kDa
Form & Buffer Supplied as a lyophilized powder.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbetaR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NF kb, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells.

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Availability: In stock

Price: €211.69
Size: 20 ug
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