Lipoprotein (a) protein (30R-3120)
Purified native Lipoprotein (a) protein
Overview
Overview
| Synonyms | Lipoprotein(a) protein, Lp(a) protein, LPA protein, AK38 protein, APOA protein, LP protein, Lipoprotein a antigen, Lipoprotein a |
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| Protein Type | Native |
| Applications | SDS-PAGE |
Specifications
| Source | Human Plasma |
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| Grade & Purity | > 95% pure |
| Molecular Weight | 280-700 kDa |
| Form & Buffer | Supplied in 50 mM Tris-HCl with 0.5 M NaCl, pH 8.2, 0.1% EDTA and 0.05% NaN3 |
Storage & Safety
| Storage | Store away from light at 2-4 deg C for 6 months |
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General Information
| Biological Significance | The physiological function of Lipoprotein a is still unknown. A function within the coagulation system seems plausible, given the aspect of the high homology between apo(a) and plasminogen. In fact, the LPA gene derives from a duplication of the plasminogen gene. Other functions have been related to recruitment of inflammatory cells through interaction with Mac-1 integrin, angiogenesis, and wound healing. However, individuals without LPA or with very low LPA levels seem to be healthy. Thus plasma LPA is certainly not vital, at least under normal environmental conditions. |
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