LIX protein (Mouse) (30R-AL014)
Purified recombinant Mouse LIX protein
Overview
Overview
| Synonyms | CXCL5 protein, ENA-78 protein |
|---|---|
| Species | Mouse |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Residues | Region of LIX protein corresponding to amino acids APSSVIAATE LRCVCLTVTP KINPKLIANL EVIPAGPQCP TVEVIAKLKN QKEVCLDPEA PVIKKIIIQK ILGSDKKKAK RNALAVERTA SVQ. |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 98% pure |
| Molecular Weight | 9.8 kDa |
| Form & Buffer | Supplied as a lyophilized powder. |
Usage & Assay Information
| Bioactivity | Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/ml. |
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Storage & Safety
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
General Information
| Biological Significance | The Mouse homolog of ENA-78 is called LIX. ENA-78/LIX is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78/LIX is a chemoattractant for neutrophils. The three naturally occurring variants of human ENA-78; ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78/LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR' motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. |
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