Loricrin antibody (70R-1177)

Rabbit polyclonal Loricrin antibody raised against the N terminal of LOR

Synonyms Polyclonal Loricrin antibody, Anti-Loricrin antibody, LOR antibody, MGC111513 antibody
Specificity Loricrin antibody was raised against the N terminal of LOR
Cross Reactivity Human
Applications IHC, WB
Immunogen Loricrin antibody was raised using the N terminal of LOR corresponding to a region with amino acids GYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSG
Assay Information Loricrin Blocking Peptide, catalog no. 33R-3685, is also available for use as a blocking control in assays to test for specificity of this Loricrin antibody

Images

Immunohistochemical staining using Loricrin antibody (70R-1177)

Loricrin antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (arrows) in Human Kidney. Magnification is at 400X

Specifications

Host Rabbit
Method of Purification Total IgG Protein A purified
Molecular Weight 35 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 100ul distilled water for a 1mg/ml concentration of LOR antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 5 ug/ml; IHC: 4-8 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance LOR is a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.LOR encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in LOR may be the cause of both Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.

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Images

  • Immunohistochemical staining using Loricrin antibody (70R-1177) | Loricrin antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (arrows) in Human Kidney. Magnification is at 400X
  • Western Blot analysis using Loricrin antibody (70R-1177) | Loricrin antibody (70R-1177) used at 5 ug/ml to detect target protein.

Availability: In stock

Price: €258.73
Size: 100 ug
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