LRDD Blocking Peptide (33R-8046)
A synthetic peptide for use as a blocking control in assays to test for specificity of LRDD antibody, catalog no. 70R-5426
Overview
Overview
| Synonyms | LRDD control peptide, LRDD antibody Blocking Peptide, Anti-LRDD Blocking Peptide, Leucine-Rich Repeats And Death Domain Containing Blocking Peptide, DKFZp434D229 Blocking Peptide, MGC16925 Blocking Peptide, PIDD Blocking Peptide |
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| Protein Type | Synthetic |
| Applications | IHC, WB |
Specifications
| Residues | RLQGNPLGEASPDAPSSPVAALIPEMPRLFLTSDLDSFPVTPQGCSVTLA |
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| Molecular Weight | 83 kDa |
| Form & Buffer | Lyophilized powder. Add 100ul of distilled water for a final peptide concentration is 1 mg/ml. |
Storage & Safety
| Storage | Store at -20 deg C long term. Avoid repeat freeze-thaw cycles. |
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General Information
| Biological Significance | The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. |
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