Ly108 antibody (PE) (61R-1313)

Mouse monoclonal Ly108 antibody (PE)

Synonyms Monoclonal Ly108 antibody, Anti-Ly108 antibody, Ly-108, Ly-108 antibody, Ly 108, SLAM Family Receptor antibody, CD antigen CD352 antibody, Lymphocyte antigen 108 antibody, Ly 108 antibody, SLAM F6 antibody, SLAMF6 antibody, Ly108 antibody, Ly108
Specificity Mouse
Applications FC
Assay Information A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest

Images

Flow Cytometric analysis using Ly108 antibody (PE) (61R-1313)

Staining of C57Bl/6 splenocytes with CD45R antibody (FITC) and 0.06 ug of Mouse IgG2a K Isotype Control (PE) (left) or 0.06 ug of Ly-108 antibody (PE) (right). Cells in the lymphocyte gate were used for analysis.

Specifications

Host Mouse
Clone 13G3-19D
Isotype IgG2a kappa
Tag/Conjugate PE
Form & Buffer Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer.
Concentration 200 ug/ml

Usage & Assay Information

Usage Recommendations FC: 0.5 ug/test

Storage & Safety

Storage Store at 2-8 deg C. Do not freeze. Protect from light.

General Information

Biological Significance The 13G3-19D monoclonal antibody reacts with mouse Ly108, the mouse homologue of human SLAMF6. Mouse Ly108 is also known as NTB-A, and is expressed on NK, T cells, and B cells. Engagement of the Ly108 receptor enhances NK cell activity and expression of IFN-gamma, and contributes to the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. CD4+ T cells from Ly108 knock-out mice exhibit diminished ability to produce IL-4 and defective neutrophil functions.Staining has not revealed any strain differences between C57BL/6 and BALB/c mice. Other strains have not been tested.

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Images

  • Flow Cytometric analysis using Ly108 antibody (PE) (61R-1313) | Staining of C57Bl/6 splenocytes with CD45R antibody (FITC) and 0.06 ug of Mouse IgG2a K Isotype Control (PE) (left) or 0.06 ug of Ly-108 antibody (PE) (right). Cells in the lymphocyte gate were used for analysis.

Availability: In stock

Price: €143.15
Size: 25 ug
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