LYN antibody (20-LS30)

Sheep polyclonal LYN antibody

Synonyms Polyclonal LYN antibody, Anti-LYN antibody
Cross Reactivity To be determined by end-user
Applications User optimized
Immunogen LYN antibody was raised in sheep using maltose binding protein fusion protein as the immunogen.

Specifications

Host Sheep
Form & Buffer IgG fraction supplied in PBS, pH 7.5, with no preservative added.
Concentration Typically 1-5 mg/ml

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles.

General Information

Biological Significance Lyn (also known as p53/56 Lyn) is a membrane associated protein tyrosine kinase (PTK) mostly expressed in hemopoietic cells which is important in cellular signaling. It contains an SH2 and SH3 domain and has been found to be cleaved after activation of caspases in apoptosis. A member of the Src family of PTKs, there are two known isoforms for Lyn which plays an indispensable role in the Fc epsilon RI (Fcer1) and the B cell IgM receptor signaling pathway and is essential for Syk activation and Lat phosphorylation after Fcer1 aggregation and can also phosphorylate Tec on multiple residues.

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Availability: In stock

Price: €224.86
Size: 250 ug
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