LYVE1 protein (Mouse) (30R-AL009)
Purified recombinant Mouse LYVE1 protein
Overview
Overview
| Synonyms | LYVE-1 protein, Lymphatic Endothelial Cell protein, LYVE 1 protein, LYVE-1 protein, Lymphatic Vessel protein, LYVE1, LYVE-1, LYVE 1 |
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| Species | Mouse |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Expression System | Sf-9 insect cells |
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| Grade & Purity | > 95% pure |
| Molecular Weight | 35-45 kDa |
| Form & Buffer | Supplied as a lyophilized powder with no preservative. Reconstitute in sterile water to a concentration > 0.05mg/ml. |
Storage & Safety
| Storage | Store at -70 deg C until reconstitution. Following reconstitution product should be aliquoted and frozen at -20 deg C. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | <0.1 ng per ug of VEGF-C |
General Information
| Biological Significance | LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. |
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