M-CSF protein (30R-AM069)

Purified recombinant Human M-CSF protein

Synonyms CSF-1 protein, Macrophage Colony Stimulating Factor protein, MGI-IM protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of M-CSF protein corresponding to amino acids MEVSEHCSHM IGNGHLQILQ QLIDSQMETA CLIEYKFVDQ EQLDDPVCYL KKAFVLVQVI IEETMRFKDN TPNANATERL QELSMKLNSC FIKDYKEQNE ACVQTYKESP LRLLEKIKNF FNETKNFLEK DWNIFSKNCN DSLAKCSSRD VVTKP.
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 18.1 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse M-NFS-60 cells is 1 x 10^5 units/mg.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance M-CSF is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness, and male and female fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation.

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Availability: In stock

Price: €211.69
Size: 10 ug
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