MAN1B1 antibody (70R-12941)

Affinity purified Rabbit polyclonal MAN1B1 antibody

Synonyms Polyclonal MAN1B1 antibody, Anti-MAN1B1 antibody, MANB 1 antibody, ER alpha 1 2-mannosidase antibody, MANB-1 antibody, MANB-1, MAN1B1 antibody, ERMan1 antibody, endoplasmic reticulum mannosyl-oligosaccharide 1 2-alpha-mannosidase antibody, MANA-ER antibody, MANB 1, Man9GlcNAc2-specific processing alpha-mannosidase antibody, MAN1B1
Cross Reactivity Human
Applications IHC-P, WB
Immunogen MAN1B1 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 414 and 699 of MAN1B1

Images

Immunohistochemical staining using MAN1B1 antibody (70R-12941)

Immunohistochemical staining of paraffin-embedded SCC25 xenograft using MAN1B1 antibody at a dilution of 1:100

Specifications

Host Rabbit
Isotype IgG
Method of Purification MAN1B1 antibody was purified by antigen-affinity chromatography
Molecular Weight 80 kDa
Form & Buffer Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration 0.84 mg/ml

Usage & Assay Information

Usage Recommendations IHC-P: 1:100-1:250, WB: 1:500-1:3000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2).

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using MAN1B1 antibody (70R-12941)</font></div>     | Immunohistochemical staining of paraffin-embedded SCC25 xenograft using MAN1B1 antibody at a dilution of 1:100
  • <div><font face=Calibri size=2>Western blot analysis using MAN1B1 antibody (70R-12941)</font></div>     | Western blot analysis of 30 ug of whole cell lysate (A: Hela) using a 7.5 % SDS PAGE gel and MAN1B1 antibody at a dilution of 1:1000

Availability: In stock

Price: €323.11
Size: 100 ul
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