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MAN1B1 antibody (70R-12941)
Affinity purified Rabbit polyclonal MAN1B1 antibody
Synonyms
Polyclonal MAN1B1 antibody, Anti-MAN1B1 antibody, MANB 1 antibody, ER alpha 1 2-mannosidase antibody, MANB-1 antibody, MANB-1, MAN1B1 antibody, ERMan1 antibody, endoplasmic reticulum mannosyl-oligosaccharide 1 2-alpha-mannosidase antibody, MANA-ER antibody, MANB 1, Man9GlcNAc2-specific processing alpha-mannosidase antibody, MAN1B1
Cross Reactivity
Human
Applications
IHC-P, WB
Immunogen
MAN1B1 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 414 and 699 of MAN1B1
Specifications
Host
Rabbit
Isotype
IgG
Method of Purification
MAN1B1 antibody was purified by antigen-affinity chromatography
Molecular Weight
80 kDa
Form & Buffer
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration
0.84 mg/ml
Usage & Assay Information
Usage Recommendations
IHC-P: 1:100-1:250, WB: 1:500-1:3000
Storage & Safety
Storage
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
General Information
Biological Significance
Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2).
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Availability: In stock
Price:
€323.11
Size: 100 ul