MAP1LC3A protein (His tag) (80R-1418)
Purified recombinant Human MAP1LC3A protein
|Synonyms||MAP1BLC3 protein, MAP1LC3A, MAPLC3A-1 protein, MAPLC3A 1, Microtubule-associated protein 1A/1B light chain 3A isoform a, LC3 protein, MAPLC3A-1, MAPLC3A 1 protein, MAP1ALC3 protein, LC3A protein, ATG8E protein|
Coomassie Blue stained SDS-PAGE of MAP1LC3A protein (His tag) (80R-1418)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-120 amino acids: MPSDRPFKQR RSFADRCKEV QQIRDQHPSK IPVIIERYKG EKQLPVLDKT KFLVPDHVNM SELVKIIRRR LQLNPTQAFF LLVNQHSMVS VSTPIADIYE QEKDEDGFLY MVYASQETFG LEHHHHHH|
|Grade & Purity||> 95% pure|
|Molecular Weight||15.1 kDa (128aa) confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, 20% glycerol and 0.1M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Microtubule-associated proteins 1A/1B light chain 3A isoform a, also known as MAP1LC3A, is one of the light chain subunits and can associate with either MAP1A or MAP1B. It plays critical roles in neuronal development and in maintaining the balance between neuronal plasticity and rigidity. MAP1LC3A is expressed as two alternatively spliced isoforms that are expressed in testis, brain, heart, liver and skeletal muscle, but are absent in thymus and peripheral blood leukocytes. Recombinant human MAP1LC3A protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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