MAP1LC3B protein (His tag) (80R-1635)
Purified recombinant Human MAP1LC3B protein
|Synonyms||ATG8F protein, MAPLC3B-1 protein, LC3B protein, MAPLC3B-1, Microtubule-associated proteins 1A/1B light chain 3B protein, MAP1LC3B, MAP1A/1BLC3, MAPLC3B 1 protein, MAPLC3B 1|
Coomassie Blue stained SDS-PAGE of MAP1LC3B protein (His tag) (80R-1635)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-120 amino acids: MGSSHHHHHH SSGLVPRGSH MPSEKTFKQR RTFEQRVEDV RLIREQHPTK IPVIIERYKG EKQLPVLDKT KFLVPDHVNM SELIKIIRRR LQLNANQAFF LLVNGHSMVS VSTPISEVYE SEKDEDGFLY MVYASQETFG|
|Grade & Purity||> 95% pure|
|Molecular Weight||16.2 kDa (140aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, 20% glycerol and 100mM NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Microtubule-associated proteins 1A/1B light chain 3B, also known as MAP1LC3B, belongs to the MAP1 LC3 family. It is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. MAP1LC3B may also be involved in formation of autophagosomal vacuoles. It is expressed primarily in heart, testis, brain and skeletal muscle. Recombinant human MAP1LC3B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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