MARCKS antibody (70R-10037)
Affinity purified rabbit polyclonal MARCKS antibody
Overview
Overview
| Synonyms | Polyclonal MARCKS antibody, Anti-MARCKS antibody, MACS antibody, FLJ90045 antibody, 80K-L antibody, PKCSL antibody, PRKCSL antibody, FLJ14368 antibody, myristoylated alanine-rich protein kinase C substrate antibody |
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| Cross Reactivity | Human |
| Applications | WB |
| Immunogen | MARCKS antibody was raised in rabbit using the C terminal of MARCKS as the immunogen |
| Assay Information | MARCKS Blocking Peptide, catalog no. 33R-4233, is also available for use as a blocking control in assays to test for specificity of this MARCKS antibody |
Images
Western Blot analysis using MARCKS antibody (70R-10037)
Western Blot showing MARCKS antibody used at a concentration of 1.0 ug/ml against Fetal Liver Lysate
Specifications
| Host | Rabbit |
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| Form & Buffer | Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer. |
| Concentration | 1 mg/ml |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by the end user |
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Storage & Safety
| Storage | Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles. |
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General Information
| Biological Significance | The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. |
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