MBP antibody (70R-2325)

Rabbit polyclonal MBP antibody raised against the middle region of MBP

Synonyms Polyclonal MBP antibody, Anti-MBP antibody, MGC99675 antibody, Myelin Basic Protein antibody
Specificity MBP antibody was raised against the middle region of MBP
Cross Reactivity Human
Applications WB
Immunogen MBP antibody was raised using the middle region of MBP corresponding to a region with amino acids FGGDRGAPKRGSGKDSHHPARTAHYGSLPQKSHGRTQDENPVVHFFKNIV
Assay Information MBP Blocking Peptide, catalog no. 33R-2903, is also available for use as a blocking control in assays to test for specificity of this MBP antibody

Images

Western Blot analysis using MBP antibody (70R-2325)

MBP antibody (70R-2325) used at 1 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Affinity purified
Molecular Weight 33 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of MBP antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells.

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Images

  • Western Blot analysis using MBP antibody (70R-2325) | MBP antibody (70R-2325) used at 1 ug/ml to detect target protein.

Availability: In stock

Price: €324.59
Size: 50 ug
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