MCL1 antibody (20R-MR001)

Rabbit polyclonal MCL1 antibody

Synonyms Polyclonal MCL1 antibody, Anti-MCL1 antibody, MCL 1, BCL2L3 antibody, MCL-1, Bcl 2 related protein EAT/mcl1 antibody, MCL 1 antibody, MCL-1 antibody, MCL1, Induced myeloid leukemia cell differentiation protein Mcl 1 antibody , BCL2 related antibody, EAT antibody, Myeloid Cell Leukemia 1 antibody, Mcl-1 antibody
Cross Reactivity Dog, human,monkey, pig, rabbit
Applications IHC, IP, WB
Immunogen MCL-1 antibody was raised in rabbit using a synthetic peptide corresponding to residues surrounding amino acid 131 of human Mcl-1 as the immunogen.

Images

Western Blot analysis using MCL1 antibody (20R-MR001)

Western Blot analysis of cell lysate using MCL1 antibody at 0.5-4 ug/ml ...

Specifications

Host Rabbit
Method of Purification MCL1 antibody was purified by affinity chromatography
Form & Buffer Supplied in PBS bufferwith 50% glycerol, pH 7.2, with 1% BSA, and 0.02% NaN3.
Concentration 0.2 mg/ml

Usage & Assay Information

Usage Recommendations IP: 0.5-4 ug/ml, IHC: 10-20 ug/ml, WB: 1 ug/ml

Storage & Safety

Storage Aliquot and store at -20 deg C for short term storage, -70 deg C for long-term storage. Avoid repeated freeze/thaw cycles.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance Mcl1 is an anti-apoptotic member of Bcl2 family originally isolated from the ML1 human myeloid leukemia cell line during phorbol ester-induced differentiation along the monocyte/macrophage pathway. Mcl1 localizes to the mitochondria, interacts with and antagonizes pro-apoptotic Bcl2 family members, and inhibits apoptosis by a number of cytotoxic stimuli. It is involved in programing of differentiation and concomitant maintenance of viability but not of proliferation.

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Images

  • Western Blot analysis using MCL1 antibody (20R-MR001) | Western Blot analysis of cell lysate using MCL1 antibody at 0.5-4 ug/ml ...

Availability: In stock

Price: €315.18
Size: 100 ug
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