MFGE8 protein (30R-3261)
Purified recombinant MFGE8 protein (His tag)
Overview
Overview
| Synonyms | Breast epithelial protein, BA46 protein, HMFG protein, MFGM protein, Milk fat globule EGF factor 8 protein, MFG E8 protein, Lactadherin protein, MFGE 8 protein, MFGE-8 protein |
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| Species | Human |
| Protein Type | Recombinant |
| Applications | ELISA, SDS-PAGE, WB |
Specifications
| Residues | 24-387 aa; Mature protein, full length |
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| Expression System | E.coli |
| Grade & Purity | > 90% pure |
| Method of Purification | MFGE8 protein was purified with Ni-affinity chromatography |
| Molecular Weight | 35 kDa |
| Tag/Conjugate | His-Sumo tag |
| Form & Buffer | Supplied in liquid form in PBS buffer with 20 mM GSH |
Storage & Safety
| Storage | Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles |
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General Information
| Biological Significance | MFGE8 plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization. Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication. 5 Medin is the main constituent of aortic medial amyloid. 5. |
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