MFGE8 protein (30R-3261)

Purified recombinant MFGE8 protein (His tag)

Synonyms Breast epithelial protein, BA46 protein, HMFG protein, MFGM protein, Milk fat globule EGF factor 8 protein, MFG E8 protein, Lactadherin protein, MFGE 8 protein, MFGE-8 protein
Species Human
Protein Type Recombinant
Applications ELISA, SDS-PAGE, WB

Specifications

Residues 24-387 aa; Mature protein, full length
Expression System E.coli
Grade & Purity > 90% pure
Method of Purification MFGE8 protein was purified with Ni-affinity chromatography
Molecular Weight 35 kDa
Tag/Conjugate His-Sumo tag
Form & Buffer Supplied in liquid form in PBS buffer with 20 mM GSH

Storage & Safety

Storage Store at 4 deg C in a working aliquot for 1 week. For long term storage, aliquot and freeze at -20 to -80 deg C, avoid repeat freeze/thaw cycles

General Information

Biological Significance MFGE8 plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization. Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication. 5 Medin is the main constituent of aortic medial amyloid. 5.

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Availability: In stock

Price: €183.23
Size: 50 ug
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