MGA antibody (10R-1241)

Mouse monoclonal MGA antibody

Synonyms Monoclonal MGA antibody, Anti-MGA antibody, MXD5 antibody, MGA antibody, MAD5 antibody, KIAA0518 antibody, FLJ12634 antibody, MAX dimerization protein 5 antibody, KIAA0518 antibody, Anti MGA antibody, MAX dimerization protein 5 antibody, MXD5 antibody, MAD5 antibody, FLJ12634 antibody
Specificity Human MGA
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen MGA antibody was raised in mouse using recombinant Max Gene Associated

Images

Western Blot analysis of immunized recombinant protein using MGA antibody (10R-1241)

Specifications

Host Mouse
Clone MGA6A4H5
Isotype IgG1
Method of Purification MGA antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer MGA antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance This gene functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor .

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Images

  • Western Blot analysis of immunized recombinant protein using MGA antibody (10R-1241)

Availability: In stock

Price: €444.17
Size: 100 ug
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