Monoclonal MGA antibody, Anti-MGA antibody, MXD5 antibody, MGA antibody, MAD5 antibody, KIAA0518 antibody, FLJ12634 antibody, MAX dimerization protein 5 antibody, KIAA0518 antibody, Anti MGA antibody, MAX dimerization protein 5 antibody, MXD5 antibody, MAD5 antibody, FLJ12634 antibody
Specificity
Human MGA
Cross Reactivity
Human. Other species not studied
Applications
Dot Blot
Immunogen
MGA antibody was raised in mouse using recombinant Max Gene Associated
Western Blot analysis of immunized recombinant protein using MGA antibody (10R-1241)
MGA antibody
Western Blot analysis of immunized recombinant protein using MGA antibody (10R-1241)
Specifications
Host
Mouse
Clone
MGA6A4H5
Isotype
IgG1
Method of Purification
MGA antibody was purified using protein G column chromatography from culture supernatant of hybridoma
cultured in a medium containing bovine IgG-depleted
(approximately 95%) fetal bovine serum.
Form & Buffer
MGA antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information
This antibody solution contains sodium azide (NaN )
as a preservative. There is a potential hazard that
NaN reacts with copper or lead to produce an explosive
compound. For safe disposal, the vial has to
be washed thoroughly with water. It is strongly adv
General Information
Biological Significance
This gene functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor .