MHC Class II antibody (FITC) (61R-1137)
Rat monoclonal MHC Class II antibody (FITC)
Overview
Overview
| Synonyms | Monoclonal MHC Class II antibody, Anti-MHC Class II antibody, MHC II antibody, IA antibody, MHCCII antibody, I-A/E antibody, I-A/E antibody, Anti MHC Class II antibody, IE antibody, MHCII antibody, IE antibody, MHC Class II antibody, IA/IE antibody, MHCII antibody, MHCCII antibody, IA/IE antibody, IA antibody, MHC II antibody |
|---|---|
| Specificity | Mouse |
| Applications | FC |
| Assay Information | ug size: has been tested by flow cytometric analysis of human peripheral blood leukocytes and should be used at the same concentration as the experimental antibody. |
Images
Flow Cytometric analysis using MHC Class II antibody (FITC) (61R-1137)
Staining of C57BL/6 splenocytes with CD3e antibody and 0.06 ug of Rat IgG2b K Isotype Control (FITC) (left) or 0.06 ug of MHC class II antibody (I-A/I-E) (FITC) (right). Cells in the lymphocyte gate were used for analysis.
Specifications
| Host | Rat |
|---|---|
| Clone | M5/114.15.2 |
| Isotype | IgG2b kappa |
| Tag/Conjugate | FITC |
| Form & Buffer | Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer. |
| Concentration | 500 ug/ml |
Storage & Safety
| Storage | Store at 2-8 deg C. Do not freeze. Protect from light. |
|---|
General Information
| Biological Significance | The M5/114.15.2 monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins. It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2b, H-2, H-2q, H-2p, H-2r and H-2u but not from mice carrying the H-2s or H-2f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2b, H-2, H-2q, H-2u but not H-2f, H-2k, or H-2s haplotypes. |
|---|
Reviews
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product