MIA antibody (70R-MR032)

Affinity purified Rabbit polyclonal MIA antibody

Synonyms Polyclonal MIA antibody, Anti-MIA antibody, Cartilage-derived retinoic acid-sensitive antibody antibody, Melanoma Inhibitory Activity antibody, CD-RAP antibody
Specificity Human MIA
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen MIA antibody was raised in rabbit using highly pure recombinant human MIA as the immunogen.

Specifications

Host Rabbit
Molecular Weight 12.2 kDa (predicted detection band MW)
Form & Buffer Lyophilized from PBS, pH 7.2.

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance MIA is the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family; MIA, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. MIA is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells that promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. Elevated levels of MIA may represent a clinically useful marker for diagnosis of melanoma metastasis as well as a potential marker for rheumatoid arthritis.

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Availability: In stock

Price: €211.69
Size: 50 ug
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