MIP1 alpha antibody (biotin) (60R-MR002bt)

Rabbit polyclonal MIP1 alpha antibody (biotin) conjugated

Synonyms Polyclonal MIP1 alpha antibody, Anti-MIP1 alpha antibody, Macrophage Inflammatory antibody-1 alpha antibody, MIP-1 alpha antibody, LD78 beta antibody, CCL3 antibody
Specificity Murine MIP1
Cross Reactivity To be determined by end-user
Applications ELISA, WB
Immunogen MIP1 alpha antibody (biotin) was raised in rabbit using highly pure recombinant murine MIP-1a as the immunogen.

Specifications

Host Rabbit
Molecular Weight 7.8 kDa (predicted detection band MW)
Tag/Conjugate Biotin
Form & Buffer Lyophilized from PBS, pH 7.2. Reconstitute in sterile PBS with 0.1%BSA to a concentration of 50 ug/ml .

Usage & Assay Information

Usage Recommendations ELISA: 0.25-1 ug/ml, WB: 0.1-0.2 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and Mouse MIP-1 alpha and MIP-1 beta are active on human and Mouse hematopoietic cells.

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Availability: In stock

Price: €305.78
Size: 50 ug
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