MIP1 beta antibody (70R-13921)
Affinity purified Rabbit polyclonal MIP1 beta antibody
Overview
Overview
| Synonyms | Polyclonal MIP1 beta antibody, Anti-MIP1 beta antibody, MIP1 beta, MIP beta 1, CCL4 antibody, MIP beta-1, MIP beta 1 antibody, MIP beta-1 antibody, MIP-1 beta antibody, Macrophage Inflammatory antibody-1beta antibody, ACT-2 antibody |
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| Applications | WB |
| Immunogen | MIP1 beta antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of Rabbit MIP1b as the immunogen |
Images
Western Blot analysis using MIP1 beta antibody (70R-13921)
Lane 1: Mouse Spleen Tissue Lysate; Lane 2: Mouse Cardiac Muscle Tissue Lysate; Lane 3: Mouse Lung Tissue Lysate; Lane 4: Mouse Kidney Tissue Lysate; Lane 5: Mouse Skeletal Muscle Tissue Lysate
Specifications
| Host | Rabbit |
|---|---|
| Isotype | IgG |
| Method of Purification | MIP1 beta antibody was purified by affinity chromatography |
| Form & Buffer | Supplied in lyophilized form |
Usage & Assay Information
| Usage Recommendations | Optimal conditions to be determined by the end user |
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Storage & Safety
| Storage | Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. |
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