MIP1 protein (80R-4323)

Purified Recombinant MIP1 protein (His tagged)

Synonyms Timp1 protein, Timp protein, TIMP-1 protein
Species Rat
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis using MIP1 protein (His tag) (80R-4323)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 24-217 aa: CSCAPTHPQT AFCNSDLVIR AKFMGSPEII ETTLYQRYEI KMTKMLKGFD AVGNATGFRF AYTPAMESLC GYVHKSQNRS EEFLIAGRLR NGNLHITACS FLVPWHNLSP AQQKAFVKTY SAGCGVCTVF PCSAIPCKLE SDSHCLWTDQ ILMGSEKGYQ SDHFACLPRN PDLCTWQYLG VSMTRSLPLA KAEAHHHHHH
Expression System Insect cells
Grade & Purity > 90% pure
Molecular Weight 22.3 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in PBS buffer (pH 7.4) containing 10% glycerol
Concentration 500 ug/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage, aliquot and store at -20 or -70 deg C. Avoid repeat freeze/thaw cycles
Endotoxin Levels < 1.0 EU per 1 microgram of protein

General Information

Biological Significance TIMP1, also known as metalloproteinase inhibitor 1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. MMP1 functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. It plays a role in integrin signaling. Recombinant rat TIMP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • 

SDS-PAGE analysis using MIP1 protein (His tag) (80R-4323)



 | 

Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: €224.95
Size: 50 ug
OR
Shipping
View Our Distributors