MIP2 protein (Mouse) (30R-AG031)
Purified recombinant Mouse MIP2 protein
Overview
Overview
| Synonyms | MIP2, GRO2 protein, MGSA beta protein, MIP 2, CXCL2 protein, MIP 2 protein, Growth Regulated protein, MIP-2 protein, Melanoma Growth Stimulatory Activity protein, Viral Macrophage inflammatory Protein-2 protein, MIP-2 protein, MIP-2 |
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| Species | Mouse |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Residues | Region of MIP2 protein corresponding to amino acids AVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKV CLDPEAPLVQ KIIQKILNKG KAN. |
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| Expression System | E.coli |
| Grade & Purity | > 98% pure |
| Molecular Weight | 7.8 kDa |
| Form & Buffer | Supplied as a lyophilized powder. |
Usage & Assay Information
| Bioactivity | Determined by its ability to chemoattract total human neutrophils using a concentration range of 1.0-10.0 ng/ml. |
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Storage & Safety
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
General Information
| Biological Significance | All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine MIP-2 is a 7.8 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. |
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