MIP3 alpha protein (Mouse) (30R-AM054)
Purified recombinant Mouse MIP3 alpha protein
Overview
Overview
| Synonyms | MIP3 alpha, MIP 3 alpha, MIP-3 alpha, Exodus-1 protein, Macrophage Inflammatory Protein-3 alpha protein, MIP-3 alpha protein, MIP 3 alpha protein, CCL20 protein, MIP-3 alpha protein, LARC protein |
|---|---|
| Species | Mouse |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Residues | Region of MIP3 alpha protein corresponding to amino acids ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM. |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 98% pure |
| Molecular Weight | 7.9 kDa |
| Form & Buffer | Supplied as a lyophilized powder. |
Usage & Assay Information
| Bioactivity | Determined by its ability to chemoattract Mouse CCR6 transfected HEK/293 cells using a concentration range of 0.1-10.0 ng/ml |
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Storage & Safety
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
General Information
| Biological Significance | MIP-3 alpha is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and signals through the CCR6 receptor. MIP-3 alpha is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. |
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