MIP3 beta protein (Mouse) (30R-AM019)
Purified recombinant Mouse MIP3 beta protein
Overview
Overview
| Synonyms | MIP beta-3, MIP beta-3 protein, ELC protein, Macrophage Inflammatory Protein-3 beta protein, MIP-3 beta protein, Exodus-3 protein, CCL19 protein, MIP beta 3 protein, MIP3 beta, MIP beta 3 |
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| Species | Mouse |
| Protein Type | Recombinant |
| Applications | User optimized |
Specifications
| Residues | Region of MIP3 beta protein corresponding to amino acids GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS. |
|---|---|
| Expression System | E.coli |
| Grade & Purity | > 98% pure |
| Molecular Weight | 9.2 kDa |
| Form & Buffer | Supplied lyophilized with no additives. Reconstitute in distilled water to 0.1-1.0 mg/ml. |
Usage & Assay Information
| Bioactivity | Determined by its ability to chemoattract activated human T cells expressing the CCR7 receptor. The ED50 for this effect is 30-90 ng/ml. |
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Storage & Safety
| Storage | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Endotoxin Levels | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
General Information
| Biological Significance | MIP-3 beta is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3 beta is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3 beta is active on Mouse cells. |
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