Mouse anti Human IgM (41R-1586)
Monoclonal Mouse anti Human IgM antibody
Overview
Overview
| Synonyms | Human IgM antibody, Anti-IgM, Mononclonal IgM antibody, Immunoglobulin M antibody, Anti Human IgM |
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| Specificity | Human IgM |
| Applications | ELISA |
| Immunogen | Human IgM antibody was raised in mouse using recombinant human IgM as the immunogen. |
Specifications
| Host | Mouse |
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| Clone | KT38 |
| Isotype | IgG1 |
| Method of Purification | Purified by Protein A Chromatography |
| Form & Buffer | Supplied as a liquidin PBS with 0.1% sodium azide as a preservative |
| Concentration | 1 mg/ml |
Storage & Safety
| Storage | Store at 4 deg Cshort term.For longer term storage, aliquot and store at -20 to -80 deg C, avoiding repeated freeze/thaw cycles. |
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General Information
| Biological Significance | Immunoglobulin M (IgM) is made up ofpentamers and sometimeshexamers, which are each comprised of two heavy-chains (mu-chains) and two light chains, bound by disulfide bonds and a J-chain. Each monomer has two antigen binding sites and so a pentameric IgM molecule has 10 binding sites anda molecular mass of approximately 900 kDa. IgM is present on B cells and functionsinthe control of B-cell activation andalso as theprimary antibody against A and B antigens on red blood cells.IgM is found in serum primarilyandin the interstitium only in very low quantities. |
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