Mouse IgG Blocking Reagent (30R-AH071)
Mouse IgG (H + L) Blocking Reagent
Overview
Overview
| Synonyms | Blocker of Human Anti-Mouse Immunoglobulin G Antibodies |
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| Species | Mouse |
| Applications | User optimized |
Specifications
| Form & Buffer | PBS, pH 7.3, with 1,000 ppm BND added as a preservative. |
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Storage & Safety
| Storage | Store at 4 deg C. DO NOT FREEZE. |
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General Information
| Biological Significance | Heterophilic Antibodies are a group of human antibodies against animal IgG. HA interference is a well known interference factor in diagnostic assays, often causing false positive results. The most known Heterophilic Antibody interference is HAMA. HA to other animals such as Goat (HAGA), Sheep (HASA), Rabbit (HARA), etc. may also cause false results. The frequency of such interference is low, but the false results have significant impact on the quality and competitiveness of the diagnostic assays as well as on the lives of those individuals who have been falsely diagnosed. Treatment of substrates with a suitable blocking agent can reduce such non-specific binding activity. |
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