MPO protein (30C-CP3028)
Purified native Human MPO protein
Overview
Overview
| Synonyms | Myeloperoxidase antibody |
|---|---|
| Species | Human |
| Protein Type | Native |
| Applications | User optimized |
Specifications
| Source | Human neutrophils |
|---|---|
| Grade & Purity | > 95% pure |
| Molecular Weight | 150 kDa |
| Form & Buffer | Lyophilized from 50mM NaC2H3O2, pH 6.0 with 100 mM NaCl. |
Usage & Assay Information
| Bioactivity | 180-220 units/mg after lyophilization - One unit of activity is defined as the amount of enzyme that will decompose one micromole of hydrogen peroxide per minute at 25o C , pH 6.1. Reaction mixture contains 33 mM sodium phosphate, pH 6.1, 30 mM guaiacol, |
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Storage & Safety
| Storage | Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles. |
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| Biohazard Information | Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests. |
General Information
| Biological Significance | Myeloperoxidase is a heme protein which catalyzes oxidations by hydrogen peroxide, including MPO- chloride mediated killing of microbes and tumor cells, inactivation of hemotactic factors, crosslinking of proteins and inclination of proteins. |
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