Polyclonal MRCK alpha antibody, Anti-MRCK alpha antibody, myotonic dystrophy protein kinase-like alpha antibody, DKFZp686P1738 antibody, DKFZp686L1738 antibody, KIAA0451 antibody, PK428 antibody, MRCKA antibody, CDC42BPA antibody, ser-thr protein kinase PK428 antibody, ser-thr protein kinase related to the myotonic dystrophy protein kinase antibody, MRCK antibody, FLJ23347 antibody, DMPK-like alpha antibody
Cross Reactivity
Human
Applications
ICC, IF, IHC-P, WB
Immunogen
MRCK alpha antibody was raised in rabbit using a recombinant protein fragment contain a sequence corresponding to a region within amino acids 373 and 564 of MRCK alpha
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
General Information
Biological Significance
The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization.