Polyclonal MTA1 antibody, anti-MTA1 antibody, MTA1, MTA 1, MTA-1 antibody, Metastasis Associated Protein 1 antibody, MTA-1 antibody, MTA 1 antibody, MTA 1 antibody, MTA-1
Applications
IHC-F, IHC-P, WB
Immunogen
MTA1 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human MTA1, identical to the related Rabbit and rat sequences, as the immunogen
Optimal conditions to be determined by the end user
Storage & Safety
Storage
Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.
General Information
Biological Significance
This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains.