This product contains 0.05 % sodium azide as a preservative, appropriate care should be taken in handling.
General Information
Biological Significance
Mucins are heavily glycosylated proteins which constitute the major components of mucus covering the surface of epithelial tissues. Nine distinct epithelial mucin genes (Muc-1, 2, 3, 4, 5AC, 5B, 6, 7 and 8) have been identified. Various immunohistochemical and in situ hybridization studies have reported that these mucins are differentially expressed in epithelia with cell-type specificity. In gastric cancer, alterations in mucin polypeptide expression have been reported, including the loss of expression of Muc-5AC glycoprotein, increased mucin heterogeneity, glycosylation changes and the expression of simple mucin-type carbohydrates.