MYL12A protein (His tag) (80R-1924)
Purified recombinant MYL12A protein
|Synonyms||MYLA-12 protein, MLCB protein, Myosin regulatory light chain 12A protein, MYL2B protein, MRLC3 protein, MYLA-12, MYLA 12 protein, MRCL3 protein, MYL12A, MYLA 12|
|Assay Information||MYL12A protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.|
Coomassie Blue stained SDS-PAGE of MYL12A protein (His tag) (80R-1924)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-171 amino acids: MGSSHHHHHH SSGLVPRGSH MGSHMSSKRT KTKTKKRPQR ATSNVFAMFD QSQIQEFKEA FNMIDQNRDG FIDKEDLHDM LASLGKNPTD EYLDAMMNEA PGPINFTMFL TMFGEKLNGT DPEDVIRNAF ACFDEEATGT IQEDYLRELL TTMGDRFTDE EVDELYREAP IDKKGNFNYI EFTRILKHGA KDKDD|
|Grade & Purity||> 90% pure|
|Molecular Weight||22.4 kDa|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, with 20% glycerol and 1mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C or -70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||MYL12A, also known as myosin regulatory light chain 12A, plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. This protein is implicated in cytokinesis, receptor capping, and cell locomotion. Recombinant human MYL12A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.|
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