Neutrophil Elastase antibody (10-2305)
Recombinant Fab monoclonal Neutrophil Elastase antibody
Overview
Overview
| Synonyms | Monoclonal Neutrophil Elastase antibody, Anti-Neutrophil Elastase antibody, ELANE antibody, ELA2 antibody, GE antibody, HLE antibody, HNE antibody, NE antibody, PMN-E antibody, SCN1 antibody, eukocyte elastase antibody, ELANE antibody, ELA2 antibody, Elastase 2 antibody, Neutrophil antibody, elaszym antibody, Serine elastase antibody |
|---|---|
| Specificity | Human |
| Protein Type | Recombinant |
| Applications | ELISA |
| Assay Information | Neutrophil Elastase antibody pair: 10-2305 can be used as the capture antibody with 10-2306 as the detection antibody for detection of human Neutrophil Elastase in ELISA |
Specifications
| Host | Mouse |
|---|---|
| Clone | M72088 |
| Isotype | IgG1 kappa - Fab fragment |
| Expression System | E.coli |
| Grade & Purity | > 95% pure |
| Method of Purification | Neutrophil Elastase antibodies screened using Phage Display system. Expressed in and purified from E. coli. |
| Tag/Conjugate | His tag |
| Form & Buffer | Supplied as liquid in 50 mM Potassium Phosphate, 10 mM Boric Acid, 150 mM NaCl, pH 7 |
| Concentration | > 1 mg/ml |
Storage & Safety
| Storage | Store at -20 deg C in small aliquots. Avoid repeated freeze thawing. |
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General Information
| Biological Significance | Neutrophil Elastase is a serine proteinase in the same family as chymotrypsin and has broad substrate specificity. Secreted by neutrophils and macrophages during inflammation, it destroys bacteria and host tissue. Neutrophil Elastase antibody was produced as a recombinant Fab monoclonal antibody in a Phage Display system. This anti-Neutrophil Elastase antibody is used for detection of human Neutrophil Elastase in ELISA. The concentration of the antibody ranges from 1 mg/ml to 25 mg/ml depending on the lot. Recombinant Fab monoclonal antibodies have a number of advantages over standard antibodies including; improved scale up for batch consistency, more efficient binding so less antibody required, more accurate binding meaning fewer conjugation issues, less non specific due to removal of the Fc region, more flexibility for purification and labeling through a C-terminal His tag. |
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Neutrophil Elastase antibody
Recombinant Fab monoclonal Neutrophil Elastase antibody