NFATc1 antibody (10R-1130)

Mouse monoclonal NFATc1 antibody

Synonyms Monoclonal NFATc1 antibody, Anti-NFATc1 antibody, NFAT 1c, NFAT 1c antibody, NFATc1, NFAT-1c antibody, NFAT-1c, nuclear factor of activated T-cells antibody, NFAT2 antibody, cytosolic component 1 isoform A antibody, NF-ATC antibody, NFATc antibody
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, WB
Immunogen NFATc1 antibody was raised in mouse using recombinant human NFATc1 (428-716aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone AT1C3
Isotype IgG2a kappa
Source Anti-human NFATc1 antibody, clone AT1C3, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NFATc1 protein.
Method of Purification NFATc1 antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:1,000-1:2,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (NFATc1) is a component of the nuclear factor of activated T cells DNA-binding transcription complex which consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. This protein plays a main role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription and functions as a major molecular target for the immunosuppressive drugs such as cyclosporine A. NFATc1 is expressed in most human primary lymphocytes and mature human T- and B-cell neoplasms.

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Availability: In stock

Price: €249.33
Size: 100 ul
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