NKRP1A antibody (10-2556)

Rat monoclonal NKRP1A antibody

Synonyms Monoclonal NKRP1A antibody, Anti-NKRP1A antibody, CD161, CLEC5B, hNKR-P1A, killer cell lectin-like receptor subfamily B member 1, killer cell lectin-like receptor subfamily B, member 1, KLRB1, MGC138614, NKR, NKR-P1, NKR-P1A, NKRP1A, Q12918 antibody
Specificity Rat
Cross Reactivity Mouse
Applications FC
Immunogen NKRP1A antibody was raised in Rat using YB2/0 rat plasmacytoma cells transfected with NKRP1 as the immunogen

Specifications

Host Rat
Clone 3B3
Isotype IgG2a
Method of Purification NKRP1A antibody purified by affinity chromatography
Form & Buffer Supplied as liquid in PBS with 0.02% sodium azide
Concentration 1 mg/ml

Storage & Safety

Storage Store as concentrated solution. Aliquot and store at -20 deg C or below. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance NKRP1A plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3.

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Availability: In stock

Price: €159.51
Size: 100 ug
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