NMDAR1 antibody (10R-8061)
Mouse monoclonal NMDAR1 antibody
Overview
Overview
| Synonyms | Monoclonal NMDAR1 antibody, Anti-NMDAR1 antibody, NMDAR 1 antibody, NMDAR-1 antibody, NMDAR1, NMDAR 1, NMDAR-1, Glutamate receptor ionotropic N-methyl D-aspartate 1 antibody, GluN1 antibody, NMDR1 antibody, NMD-R1 antibody, NMD R1 antibody, GRIN1 antibody, NR1 antihody, NMDA 1, NMDA-1, NMDA 1 antibody |
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| Specificity | Recognizes an epitope between amino acids 660-811 of the NMDAR1 receptor |
| Cross Reactivity | Human, Rat, Monkey, Xenopus. No cross-reactivity with NMDAR2, NMDAR3, NMDAR4 or NMDAR5 |
| Applications | ELISA, ICC, IHC, IHC-P, RIA |
| Immunogen | NMDAR1 antibody was raised in Mouse using recombinant fusion protein containing GST and NMDAR1 aa. 660-811 as the immunogen |
Images
Western Bot analysis using NMDAR1 antibody (10R-8061)
Immunoblots using NMDAR1 antibody (1:1000) to detect oocytes expressing either wt or NMDAR1 mutant receptors. M1 indicates the expected band position of the NMDAR1 monomer (~110 kDa) and D1, the NMDAR1 homodimer (~220 kDa). * indicates non-specific bands seen with the NMDAR1 antibody.
Specifications
| Host | Mouse |
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| Clone | 54.1 |
| Isotype | IgG2a |
| Method of Purification | NMDAR1 antibody was purified by Protein A chromatography |
| Form & Buffer | Supplied in PBS buffer with no preservative |
Usage & Assay Information
| Usage Recommendations | IHC: 1:500-2000; WB: 1:500per 50 ug protein |
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Storage & Safety
| Storage | Ships on dry ice. Upon receipt store at -20°C. Avoid repeat freeze-thaws. |
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General Information
| Biological Significance | NMDAR1 a subunit of N-methyl-D-aspartate (NMDA) receptors, members of the glutamate receptor channel superfamily. Possesses high calcium permeability and voltage-dependent sensitivity to magnesium and is modulated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. Mediates neuronal functions in glutamate neurotransmission. |
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