NME3 protein (His tag) (80R-1647)
Purified recombinant Human NME3 protein
|Synonyms||NME 3 protein, Nucleoside diphosphate kinase 3 protein, NDPK-C protein, NME3, c371H6.2 protein, NDPKC protein, NM23H3 protein, NME-3 protein, NME-3, DR-nm23 protein, Non-Metastatic Cells 3, NME 3, NM23-H3 protein, KIAA0516 protein|
Coomassie Blue stained SDS-PAGE of NME3 protein (His tag) (80R-1647)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||22-169 amino acids: MGSSHHHHHH SSGLVPRGSH MERTFLAVKP DGVQRRLVGE IVRRFERKGF KLVALKLVQA SEELLREHYA ELRERPFYGR LVKYMASGPV VAMVWQGLDV VRTSRALIGA TNPADAPPGT IRGDFCIEVG KNLIHGSDSV ESARREIALW FRADELLCWE DSAGHWLYE|
|Grade & Purity||> 95% pure|
|Molecular Weight||19.1 kDa (169aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 50% glycerol, 0.1M NaCl and 2mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||NME3 is a potential suppressor of metastasis, expressed at a much lower level in highly metastatic cells than in cells with lower metastatic potential. It is important for the synthesis of nucleoside triphosphates and may play a role in apoptosis induction and hematopoiesis. It is preferentially expressed during early stages of myeloid differentiation of highly purified CD34+ cells. Recombinant human NME3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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