NNT1 antibody (70R-NR011)

Affinity purified Rabbit polyclonal NNT1 antibody

Synonyms Polyclonal NNT1 antibody, Anti-NNT1 antibody, NNT-1 antibody, NNT 1 antibody, Cardiotrophin-like cytokine antibody, NNT-1 antibody, NNT-1, NNT 1, NNT1, Novel Neurtrophin-1/B-Cell Stimulating Factor-3 antibody
Specificity Human NNT1
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen NNT1 antibody was raised in rabbit using highly pure recombinant human NNT-1/BCSF-3 as the immunogen.

Specifications

Host Rabbit
Molecular Weight 22.4 kDa (predicted detection band MW)
Form & Buffer Lyophilized from PBS, pH 7.2.

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance NNT-1/BCSF-3 is a neurotrophic factor with B-cell stimulating capabilities. Expressed in lymph nodes and spleen, NNT-1/BCSF-3 binds and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member beta (LIFR-beta) and induces tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss and B cell hyperplasia associated with increased in serum IgG and IgM.

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Availability: In stock

Price: €211.69
Size: 50 ug
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